诺华诺德宣布暂停所有炎症性疾病药物研发

摘要:  Bagsvrd, Denmark, 2 September 2014 – Novo Nordisk today announced a decisionto discontinue all its research and development (RD) activities within inflammatorydisorders while increasing its efforts w ...

Bagsværd, Denmark, 2 September 2014 – Novo Nordisk today announced a decision
to discontinue all its research and development (R&D) activities within inflammatory
disorders while increasing its efforts within diabetes prevention and treatment, obesity
and diabetes complications.
The decision to discontinue all R&D within inflammatory disorders follows a review of
Novo Nordisk’s strategic position in the therapeutic area after the recently announced
discontinuation of the company’s most advanced compound, anti-IL-20 for the treatment
of rheumatoid arthritis.
“The discontinuation of anti-IL-20 delays our earliest possible entrance into the market
for anti-inflammatory therapeutics to the late 2020s,” said Mads Krogsgaard Thomsen,
executive vice president and chief science officer of Novo Nordisk. He continues:
“Significant unmet opportunities remain within diabetes, including prevention, obesity
and diabetes complications. We have therefore decided to further increase our R&D
efforts within diabetes which is our main business area.”
The decision will directly impact approximately 400 employees. Novo Nordisk currently
estimates that it will be possible to offer other positions within the company to more than
half of the affected employees. The company has initiated negotiations with the relevant
local unions regarding redundancy plans.
Novo Nordisk expects that all ongoing clinical activities within inflammatory disorders will
be finalised within the coming 6 months. After closure of the clinical trials, patients will
be followed in accordance with the protocol and further treatment will be the
responsibility of their doctors and according to local practices.
Financial implications
As a consequence of the discontinuation of all R&D activities within inflammatory
disorders, the company expects to incur a non-recurring cost of around 700 million
Danish kroner in 2014. Of this around 400 million Danish kroner relates to impairment of
intangible assets, and around 300 million Danish kroner relates to other exit costs such
as project closures and severance payments.

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